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To evaluate the accuracy of cystoscopy and cytology in predicting the histopathologic features of suspicious cystoscopic lesions. We reviewed the bladder biopsy records at two institutions from July 2001 to July 2004. Intraoperative biopsies were performed for positive (papillary or sessile) (n = 155) and equivocal (n = 101) lesions found during office cystoscopy. The specimens were submitted for...
To examine whether an association exists between body mass index (BMI) and prostate cancer detection rates or pathologic features of cancer in Japanese urologic patients. We studied the age, BMI, and biopsy results of 481 patients who underwent transrectal prostate biopsy. They were stratified by BMI into three groups according to the cutoffs recommended for Asian populations: normal, BMI less...
In adults, 10% of pheochromocytomas are extra-adrenal. Most extra-adrenal pheochromocytomas occur in the organ of Zuckerkandl. Occasionally, pheochromocytomas can arise from paraganglion chromaffin cells in other locations. We present the case of a 63-year-old hypertensive man with a periprostatic pheochromocytoma. Our patient underwent surgical extirpation of the pheochromocytoma, while sparing the...
To determine whether bladder histopathologic changes, detrusor leak point pressure (DLPP), disease duration, and preoperative catheterization time can predict for upper urinary tract (UUT) deterioration in patients with overactive neurogenic bladder dysfunction (ONBD). A total of 39 patients (7 women and 32 men) with ONBD who were treated with augmentation cystoplasty were included in the study...
To evaluate whether a recombinant replication-deficient adenovirus containing the secreted human interferon alpha-2b gene (rAd-IFN) could improve the tissue and urine levels of IFN protein by transducing the urothelium with the secreted human IFN-alpha gene. We also assessed whether varying the interval between rAd-IFN/Syn3 treatments would improve the duration and levels of gene expression. The...
To present our experience using balloon dilation and discuss secondary techniques to establish a percutaneous tract when balloon dilation fails. Balloon dilation is a safe and effective method to achieve percutaneous renal access, but it is not uniformly successful. Also, the failure rate and risk factors have not been well documented. We retrospectively reviewed our last 99 consecutive percutaneous...
Patients with implanted electrical devices such as cardiac pacemakers and cochlear implants typically must have the device inactivated before surgical procedures in which the use of electrocautery is possible. In situations in which the patient cannot tolerate inactivation of the device even for a short while, the use of a bipolar energy source may allow performance of the procedure without inactivating...
To report the development of a novel, simple-to-use method for laparoscopic deployment of fine-quality saline ice slush by way of a 10-mm end-effector for laparoscopic parenchymal hypothermia. A mechanism for making fine ice slush was created, and a 10-mm laparoscopic end-effector was designed and constructed for deployment of the ice slush. The novel ice slush deployment system was tested in a...
To compare the protective effects of grape suspensions prepared in an aqueous vehicle with grape suspensions prepared in an 8% ethanol vehicle in rabbits subjected to partial outlet obstruction. The hypothesis was that the presence of ethanol would increase the absorption of the beneficial components of the grape suspensions and thus increase their protective ability. The use of ethanol in these studies...
To evaluate whether disease severity influences quality of life using the Incontinence Quality of Life questionnaire and to determine the factors that effectively reflect disease severity in women with stress urinary incontinence (SUI). A total of 109 women (mean age 54.9 years, range 31 to 77) with UI were included in the primary analyses. Data from the responses to the Incontinence Quality of...
To report the first significant experience with the use of tissue expanders in phallic reconstruction. Patients who have undergone multiple failed surgical procedures for repair of hypospadias or epispadias often have minimal residual skin available for additional reconstructive efforts. Although a variety of graft options exist, local skin expansion can provide pigment and texture-matched skin for...
To evaluate the feasibility and efficacy of robotic-assisted laparoscopic pyeloplasty. Laparoscopic pyeloplasty has been shown to have a success rate comparable to that of the open surgical approach. However, the steep learning curve has hindered its acceptance into mainstream urologic practice. The introduction of robotic assistance provides advantages that have the potential to facilitate precise...
To evaluate the utility of a portable, at-home, low-cost, camera-less laparoscopic trainer to provide laparoscopy training inexpensively and outside the constraints of the hospital environment. Twenty-two urology residents (postgraduate year 1 to 7) were tested prospectively on four basic laparoscopic tasks on a standard video laparoscopic trainer (pretest). Objective and subjective data were collected...
To examine biochemical progression-free survival (PFS) rates as a function of preoperative prostate-specific antigen (PSA) in patients with clinical Stage T1c prostate cancer treated with radical prostatectomy. Controversy exists about whether performing prostate biopsies for PSA levels in the 2.6 to 4.0 ng/mL range provides a PFS advantage compared with detection at higher PSA ranges. A total...
To compare the surgical outcomes after radical prostatectomy between men younger than 50 years and men 50 years old or older. Between October 1, 2000 and December 31, 2003, 790 men underwent open radical retropubic prostatectomy by a single surgeon. The intraoperative, perioperative, and postoperative parameters were recorded in real time and entered into a database. The outcomes were compared...
To evaluate the effect of vascular endothelial growth factor (VEGF) on regeneration of the bladder acellular matrix graft (BAMG). A total of 40 female rats were divided into two groups. In the experimental group (VEGF+), the BAMG was incubated in VEGF and VEGF was injected into the host bladder. In the control rats, sterile solution replaced VEGF. Urodynamic studies were performed at grafting and...
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